Diet- Induced Disease Models

Research Diets has pioneered and developed proprietary methods for pelleting open source,
high fat diets for laboratory animals. We can formulate and pellet diets with up to 60 kcal%
fat, containing varying types of fats and carbohydrates. It has been our long standing practice to
work side by side with the researcher to formulate diets that will meet their needs. The "Original High Fat" diets being used in diet induced obesity studies are the D12450B, D12451, & D12492 DIO series.

D12450B - 10 kcal % Fat - DIO (LFD) Control Diet
D12451 - 45 kcal % Fat- DIO (HFD)
D12492 - 60 kcal % Fat- DIO (VHFD)

These same DIO diets are used by the top commercial breeders who are providing DIO mice and rats to the research community. See JAX Diet Induced Obesity (DIO) Services.

D12451 and D12492 have been used to induce obesity in Charles River Laboratories C57BL/6 mice.
Diet # D12451 and D12492 have been used to induce obesity in Charles River Laboratories CD rats.

Contact our Resource Center for valuable insight from years of product experience and publications in the field of obesity. Let us formulate the diets to meet your specific study needs
because, this is what we do.