OpenSource Diets - A product of Research Diets, Inc. - Lab Animal Diet and Atherosclerosis

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Lab Animal Diet and Atherosclerosis

Atherosclerosis develops from a
complicated interaction of genetic and
environmental factors. Increased risk for
Coronary Artery Disease is associated
with hyperlipidemia, obesity, diabetes,
hypertension, and insulin resistance.
Diet composition is a major factor in the
etiology and progression of all of these
diseases. Treatment of these conditions

Diet- Induced Disease Models

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>Obesity
>Diabetes
>Metabolic Syndrome
>Cancer
>Osteoporosis
>Atherosclerosis
>Hypertension

requires modification of diet as well as pharmacological
intervention. Some dietary constituents of interest, such as
antioxidants, are anti-atherogenic.

Research Diets products are routinely used in the study of atherosclerosis and its co morbid
disorders in laboratory animals. Our OpenSource diets are custom made to induce disease
phenotype expression in your animal model to address your specific research questions. For
example, the quantity and species of lipid classes present in diet affect the onset and
progression of plaque development and hyperlipidemia in many models.

Contact our Resource Center for valuable insight from years of product experience and
publications in the field of atherosclerosis. Let us formulate the diets to meet your specific study
needs because, this is what we do.

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